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Buy Primaquine
This drug is in the category: "General Health"
Primaquine is an antimalarial drug. The exact way that primaquine works is unknown.
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Before you buy, read the description of the drug.
Dosage form Primaquine:
Tablets
Pharmacological effect of Primaquine:
Antimalarial drug derived from the group of 8-aminohinolina. It is characterized by intercalation with the DNA of parasites, leading to a breach of the synthesis of nucleic acids. Shows high activity against exo-forms of all types of malaria, including pervichnotkanevye and paraeritrotsitarnye form. Particularly active against pervichnotkanevyh form Plasmodium falciparum. Has expressed gamotropnoe action: inhibits gamonty all kinds of malaria (Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae), resulting in the development cycle in the mosquito is interrupted. Shizontotsidnoe effect is expressed very weakly.
Indications Primaquine:
Malaria (three-, four-and tropical - long-term prevention of recurrence); personal and social chemoprophylaxis (in combination with chloroquine).
Contra Primaquine:
Hypersensitivity, acute infectious diseases (except malaria), granulocytopenia, rheumatism, diseases of the blood and organs of hematopoiesis CRF stenokardiya.C caution. Deficiency of glucose-6-phosphate dehydrogenase, anemia.
Side effects of Primaquine:
Abdominal pain, dyspepsia, cardialgia, fatigue, cyanosis (methemoglobinemia), inhibition of bone marrow hematopoiesis, allergic reactions, acute intravascular hemolysis with hemoglobinuria, fever against the background of hemoglobinuria (patients with deficiency of glucose-6-phosphate dehydrogenase).
Dosing and Administration Primaquine:
Inside, in a daily dose for adults and children over 15 years - 27 mg for children under 1 year - 2.25 mg, 1-2 years - 4.5 mg, 2-4 years - 6.75 mg, 4-7 years - 9 mg, 7.12 years - 13.5 mg, 12-15 years - 18 mg. The course of treatment - 2 weeks.
Special instructions Primaquine:
During treatment, regularly monitor blood tests and urine at the first sign of change in urine color, a sharp decrease in Hb or WBC count drug immediately overturned. With special care (daily dose not exceeding 15 mg of calculations based on = 27 mg for an adult diphosphate) to appoint people from the Mediterranean, the Caucasus and Africa, where frequent congenital deficiency of glucose-6-phosphate dehydrogenase; during the treatment, careful monitoring of patients .
Interaction Primaquine:
Mepakrin, sulfonamides increase toxicity. Drugs, which suppress bone marrow hemopoiesis, increased the risk myelosuppression.
